Everyone has market access to fruta planta  products on the market.Copies of the A9-of THC and endogenous cannabinoids stimulate appetite and food in the animal model experiments absorption [12,13]; U.S. New York City, St. Luke \ ‘of S. Roosevelt Hospital researchers, a study found that the cause of obesity, especially abdominal. Of fat deposition is an important reason for this is that the endocannabinoid system in the human body is over-excited, this role recognized. Is due to the A9-of THC activate brain cannabinoid l-type (CBl) receptors, so that lipogenesis accelerated. Studies have. Confirmed the expression of regional and appetite regulation of the the hypothalamus CBl receptor is closely related to the [14l, the specificity CBl receptor antagonist.
Researchers have already tackled complex problems regarding    meizitang     products.Agent can block the binding between the endogenous cannabinoid CBI receptor, leading to weight loss series with obesity. Related to body function improvement; Animal experiments have shown that, after fasting 18 h, knock addition to CBl receptor gene after small. Mice compared with wild-type eating less, even with high-fat diet, body weight and food intake is still reduced in pancreatic blood. Insulin and leptin levels also decreased, suggesting that CBl receptor of excitement in the diet-induced obesity in the development of. Play an important role [51. . 1.3.1 cannabinoid receptor type. . Cannabinoid receptors cannabinoid substances such as A9-of THC receptor response is clear cloning was.
To the cannabinoid receptor (CBR), a total of two kinds: CBl receptor and CB2 receptor. 1990 for the first time to obtain a rat. CBl receptor cDNA encodes a 473 amino acid transmembrane single peptide chain composed of the outer membrane of N. The end of several. Glycosylation sites, C. Before long,  fruta planta reduce weight  will probably be associated with health care. The terminal is located in the membrane, if the spiral form of the formation of transmembrane segments during seven hydrophobic regions,. Structural characteristics very similar to the G protein-coupled receptor family, the molecular weight of approximately 52,800. CBI receptor main. To be distributed in the central nervous system, especially the cerebral cortex, hippocampus, basal ganglia and cerebellum, it.
Brain, high expression levels, once known as the "brain-type cannabinoid receptors [16], recent studies have found CBl. Receptors are also in the peripheral tissues expression, such as the gastrointestinal tract, eye, prostate, and placenta [17]. CB2 receptor structure and. CBI similar, containing seven hydrophobic transmembrane region, is a Gl-coupled receptors, but less in the membrane PI’N end 83 amino. Acid, and both total length of only 44% identity [8]; of CB2 receptor distribution in the peripheral immune-related organizations and. Cells play an immunomodulatory effects, few studies it has been reported; In addition to the above two receptors. Experts will carefully design new    meizitang     so that it will better help people.
That there is a third receptor CB3 [19'221, but its sequence has not yet been cloned.  1.3.2 cannabinoid ligand type. For the treatment of obesity, eating behavior therapy, surgery and medication. For most. The number of obese patients, reducing energy intake and increase the sport is not enough, and often stop less. Higo weight rising rapidly, even more than before the weight loss of body weight; the choice of surgery (usually vertical. Banding gastroplasty and gastric bypass) also feel that the risk is too high, not easy to accept; a result, many obese patients. Drug therapy as the preferred l "]. Weight-loss drugs can be divided into two categories: a central nervous system acting drugs, and other non-central nervous.    meizitang     has enjoyed a stable relationship with obesity.
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